Recent Trends in Ocular Drug Delivery: A Short Review

Ocular drug delivery has been a major challenge for scientists due to its unique anatomy and physiology which contains various types of barriers such as different layers of cornea, sclera and retina including blood aqueous and blood–retinal barriers, choroidal and conjunctival blood flow etc. These barriers cause a significant challenge for delivery of a drug alone or in a dosage form, especially to the posterior segment of the eye. To overcome these problems various types of dosage forms such as nanoparticles, nanomicelles, liposomes and microemulsions have been developed. Novel drug delivery strategies such as in situ gels were developed to sustain drug levels at the target site for a sufficient time. Drug delivery via ophthalmic route has proved significant advancement for future perspectives.